Thursday, January 30, 2020

Female characters Essay Example for Free

Female characters Essay The Kite Runner by Khaled Hosseini is a novel published in 2003 which tells the story of Amir, a young Afghan boy with a traumatic past, a guilty conscience, a war-stricken homeland and a broken future. The Kite Runner explores many different issues throughout the novel; one such issue is the representation of females. Females can be seen as â€Å"material goods†, and are often shown as marginalized, weak, demeaned, and subject to many double standards in todays society, and throughout earlier history. The Kite Runner shows the idea of female representation through the development and construction of make and female characters, combined with the setting and culture in the novel. The idea of marginalized female representation is also shown in other texts such as A Lot to Learn, and Hamlet, all of which used character construction to portray these ideas. The Kite Runner portrays the idea of females as being marginalized in many different cases. There are only two females that have any backstory or focus in the book The Kite RunnerAmir’s wife Soraya, and Soraya’s mother. Hassan’s wife is also mentioned briefly. The fact that women are not focused on, and barely mentioned in the novel also show that in Afghan culture, women do not play a large role, they simply blend into the background and do as they are told. Hassan’s wife, Farzana, is described as a ‘shy woman’, ‘courteous’, and spoke in a voice just ‘barely higher than a whisper’. It seems that she cooks, cleans, and does most of the basic housework. The fact that she is so shy, polite, and quiet shows how women have been brought up in this culture. Farzana has been brought up to obey men, and to speak only when spoken to, to be polite and courteous, and to always be virtuous. The only time Farzana stood up for herself, and her family, was when Hassan was shot by the Taliban. She ‘came screaming and attacked them’ and the Taliban promptly shot her. The fact that the men could so easily and quickly shoot a woman, who was simply defending her house and family, shows again the way that women may be seen as almost worthless in the Afghan society. Soraya Taheri, Amir’s wife, on the other hand, was the complete opposite of Farzana. When we first meet Soraya, she is described as a ‘slim-hipped beauty’, ‘decent’, ‘hardworking and kind’, with a ‘princess-like’ beauty to her, and she speaks with confidence, which is unlike all of the other Afghan women described in the story. Soraya has a past that she, and everyone around her, is ashamed of. After arriving in America, Soraya saw the care-free environment, the way that women were accepted, and Soraya realized that maybe she herself could have independence too. Soraya ran away to Virginia at the age of 18; she was ‘rebellious’, she felt that she should be allowed to be independent. When she returns to her family and moves to California, the rumours spread like wildfire. All of the Afghanis here about Soraya’s shameful act, and everywhere she goes, whispers follow her. No suitable suitors appear at her doorstep, and no one forgets her ‘mistake’. ‘Its so fucking unfair’, she says, and it really is. A double standard in this society, where the men can do whatever they please and ‘no one does a god damn thing’, and when a woman does something of the same nature, they are shunned. There is a small amount of talk about Baba’s wife, who died giving birth to Amir. The Afghan community claimed that Baba would never be able to marry a woman like her; she was virtuous, clever, studying at university, and to to pit all off, she was of royal blood. Baba finally does marry this woman though, and refers to her as his ‘princess’. The way that this marriage is described accentuates the idea that men want women the way they would want material goods. The marriages are described almost as if the men are simply picking an object, and showing said object off to the world. Gertrude is seen as unequal to the the almost all-male cast. Gertrude is a female character from Shakespeare’s famous play Hamlet. The play is set in Denmark, early 14th century, and tells the story of a young prince, Hamlet, who gets a visit from his dead father’s ghost, and realizes that not all is right in the state of Denmark. Gertrude is Hamlet’s mother, and the queen of Denmark. After the death of her husband King Hamlet, Gertrude quickly remarries to the King’s brother Claudius. Hamlet depicts this sudden remarriage as betrayal, unfaithfulness, and the breaking of ‘sacred vows’. He feels disgusted that his mother would grieve so little, and move on so fast, and hatred for his mother beings to grow. The play Hamlet has been created so that we, as readers, see Hamlet’s point of view, but we do not see the way that the other characters think. I believe that this sudden remarriage was not simply because Gertrude was seduced, but because Gertrude could not hold her position of â€Å"power† without a male by her side. If we had Gertrude’s side of the story, I think we would realize that there were other motives to Gertrude’s marriage to Claudius. Gertrude could not run the state of Denmark, or even the castle, without a man in power with her; in the time Hamlet was set in, women were often demeaned, and were never seen as equals. To keep the state functioning as a whole, Gertrude realized she would need a new king to rule. Gertrude also may have realized how easy it would be for another man to take advantage; if they controlled Gertrude, they could control the state. Her marriage to Claudius at least guaranteed that the state was run by someone she trusted and could see as a ruler. None of these ideas were explicitly stated, because Gertrude was never really given a chance to defend herself and her actions, due to Hamlet being the focus of the story. ‘Frailty, thy name is woman’, Hamlet says, referring to poor Gertrude. He refers to the way that Gertrude was moulded so quickly to another’s will, the way her confidence faltered so soon, and how weak Gertrude really was. Hamlet is a character that has no respect for women. He holds a grudge against his mother, and as the play progresses, these dark feelings that he feels towards his mother grow stronger. Hamlet starts to feel so strongly to his mother ‘betraying’ him, that he starts to apply this idea to all women, even weak Ophelia. He seems to be under the impression that, though women are frail, weak, and delicate, all women deceive and take part in treachery. He does love Ophelia, but in the end, he feels that Ophelia would betray him, as all women do. He is applying a stereotype to all women, saying that they are will of weak and physical being, and treacherous at heart. Ophelia is also doted on quite a lot by her father and brother. Both men lecture Ophelia about staying virtuous, warning her not to ‘lose her heart’, but this is, again, a double standard. Laertes especially is being quite the hypocrite, since he, as a young man, would have been messing around with many young girls, and not had it held against him since it was socially accepted for men. Polonius also lectures Ophelia to keep her chastity, and talks to her as one would talk to a young child. He depicts Ophelia as being weak, innocent, nothing more than a child, and often gloats to the King Claudius about how ‘dutiful’ and ‘obedient’ Ophelia is as a daughter, as if she has no will of her own. He seems to be demeaning her, without even consciously meaning to, and Ophelia takes no offense to it; in that day and age, girls were simply brought up to accept it. ‘The object Ophelia’, Hamlet refers to Ophelia at one point. He says this the way he would say ‘the object of his affections’. He seems to be referring, yet again, to material goods, to objects, as if Ophelia is simply another prize he can add to his trophy cabinet. He also uses a great deal of sexual innuendos when around Ophelia, but neither Ophelia or any other members of the court find it offensive or out of context. He lays his head upon her lap and whispers comments that are obviously making her uncomfortable, but Ophelia never objects, simply because it was normal for women to be taken advantage of. Just like Ophelia being referred to as an object, the short story A Lot to Learn depicts an innocent girl as yet another material good. A Lot to Learn is a story about Ned Quinn, a scientist that has created the Materializer, a large machine that can create anything at the push of a button. The story tells the tale of Ned experimenting with the machine, and wishing for a girl. Before Ned mutters the word ‘girl’, he wishes for ‘money’, then a ‘martini’, then ‘beer’. These are two stereotypical goods that a person would probably wish for if he could have anything; money and alcohol. When Ned wishes for this girl, after wishing for two in-demand material goods, he seems to be sending a subtle message that perhaps he sees women as nothing more than objects of desire, yet another material good instead of a sentient being. If his experiment was a success, Ned would most likely hold on to this girl the way one would hold onto a trophy; a record of his achievements, simply for memories sake. The idea of being nothing more than an object is terribly demeaning, and another show of dominance from males. Women are very subtly discriminated and marginalized in this short story. As well as the idea of the girl being simply an object, Ned seems to be under the impression that this girl would obey him. Before wishing for a girl, Ned did not stop to think that maybe the girl would scream, or run in terror, or struggle; he simply assumed that the girl that appeared would obey. This is a show of Ned believing that women are weak both physically and mentally. This shows an immediate message about dominance, the way that Ned believes that this girl would do exactly as he wished. He seemed to be under the impression that because he was a man, he is strong, powerful, and has a sense of dignity and respect, therefor meaning that the woman that he expected to appear would simply obey. Ned seems to be very confident in himself and his invention. Though he is nervous as he wishes for each new object, he seems to be under the impression that everything will turn out fine. Ned comes across a slight hitch, however, when he mutters the word ‘girl’. In our society today, the word ‘girl’ often refers to woman, not literally a girl or child. Its a misconception, just a word in our culture that has developed to mean something else from the original meaning. Ned obviously does not want the small, innocent child that appears in the machine, as he curses ‘Hell! ’. Referring to a woman as ‘girl’ is almost demeaning in a way. The fact that Ned wishes for a girl as well is slightly disturbing. Upon reading it, most people would immediately assume that Ned wants this girl for nefarious purposes, to fulfil a fantasy or something of that drift. This is another symbol of the female representation being marginalized, shoved aside as the weaker gender. All of these different characters from these three stories easily show the idea of females being marginalized and disenfranchised. Characters such as Ned Quinn, Hamlet, and General Sahib are constructed to be dominant over the female characters. The settings and culture, when combined with these strong male characters, show the many double-standards that exist between females and males, and also show the idea of females being represented as trophy objects.

Wednesday, January 22, 2020

Illegal Immigrants Threaten the American Economy Essay -- Illegal Immi

The subject of illegal migration into the United States is a very controversial and challenging issue; but overall America’s systematic approach for regulating illegal immigrants entering our country has failed. It pertains to millions of individuals and families journeying to the bulls-eye country of America without proper documentation; but it also consists of people entering the country legally, but they violate the terms of their approved visas and passports by permanently residing here, rather than the allotted time frame they’re given. Amazing enough, The Federation For American Immigration Reform or better known as FAIR, estimated that in 2007, â€Å"the illegal immigrant population seated well above 13 million people.† Also considering this massive number grows roughly by â€Å"as many as 500,000 people every year,† across the United States; therefore a more efficient way of controlling our population needs to be effectively put into action. But wh y would these aliens risk so much to inhabit and live in the United States? It doesn’t involve too much cognitive ability to understand that under the unsatisfactory circumstances of poverty, economic deficiencies, and high unemployment rates, many will do whatever it takes to pursue the American Dream. Despite the dangers and risks that could potentially arise from crossing the border, to these illegals, the benefits of successfully migrating outweigh the costs. (www.fairus.org/site/news2) An interesting law has passed merely a few weeks ago within the state of Arizona. With our government cracking down on the illegal flow by increasing more stadium lights, fences, and man power throughout Southern California, and Texas, it has â€Å"forced a shift in the flow of illegal immigrants that ... ...ection rates than that of the United States. To make matters worse, an emergence of a Multi-Drug-Resistant strain of Tuberculosis formed three years ago (MDR-TB) and can leave a patient with over a million dollars in medical fee’s, while only a fity percent of patients going under specified treatment survive. It’s rather unfortunate, but America cannot withstand the burden of financial bills for treating the world’s diseased, ill, sick, and infected population. The government should make protecting its citizens from the catastrophic diseases brought in from illegal immigrants around the globe. How many more school children will have to be infected from catching TB before something is done? What’s the purpose of screening legal aliens for diseases that are contagious if the illegals can roam our country and infect our fellow citizens? www.fairus.org/site/news2

Tuesday, January 14, 2020

Next Generation DNA Sequencing Technologies Biology Essay

Motivation: Recent technological promotions in the field of genomics have resulted in Following Generation DNA Sequencing Technologies. These engineerings have created ballyhoo among scientists since they enable inexpensive and faster sequencing of the DNA as compared to traditional methods. Data Analysis, Genome sequencing and alliances have now become easier due to the NGS. NGS are deriving the market twenty-four hours by twenty-four hours and there is a ferocious competition amongst companies to capture the market of bioinformatics. Nevertheless, NGS does hold some mistake profiles ; yet they have managed to revolutionise the field of bioinformatics and the perceptual experience of scientists on research and genome sequencing.debutDeoxyribonucleic acid sequencing has gained much popularity since 1977 when the sequencing method of Maxam and Gilbert every bit good as the Sanger sequencing method came to visible radiation ( Hutchison III, 2007 ) . However, the Sanger sequencing engin eering was more widely accepted and has captured the market for the past 20 old ages ( Metzker, 2010 ) . The Sanger engineering besides known as the dideoxy method ( Casals et al. , 2011 ) , played a important function in decoding the whole genome sequence and harmonizing to Metzker ( 2010 ) this technique has contributed to a batch of major accomplishments, viz. the Human Genome Project amongst many others. Bateman & A ; Quackenbush ( 2009 ) even back up that the major milepost of the Human Genome Project was the coming of panoply of new engineerings that emerged from sequencing the first mention genome and engineerings that enabled the DNA sequencing instead than completing the sequencing of the whole genome. It is true that the dideoxy method has been around for rather some clip now, but due to its restrictions and the new technological promotions, novel and more robust engineerings known as the Following Generation Technologies have seen the visible radiation of the twenty-four hours. The Sanger engineering is classified as the first coevals engineering and the latest engineerings developed for sequencing genomes fall in the class of Following Generation Technologies ( Metzker, 2010 ) . The chief advantage of the Following Generation Sequencing Technology is the fact that the genome can be sequenced in analogue, therefore bring forthing a larger figure of reads as compared to the Sanger method and in a much shorter sum of clip ( Hutchison III, 2007 ) . The high efficiency of the newer engineerings consequences from the fact that they use the latest instruments like high declaration imagination and more efficient algorithms amongst others. In general, the Following Generation Technologies use shorter reads to fix the procedure of sequencing ( Hutchison III, 2007 ) ; nevertheless, this raises the inquiry of whether the assembly of the short single reads is accurate plenty to bring forth the right sequence. From a scientific point of position, a larger figure of reads implies a greater coverage across the genome and therefore histories for the good truth in the genome assembly of the Following Generation Technologies. Hutchison III ( 2007 ) agrees to the fact that this is one of the grounds behind the truth and celerity of the newer engineerings. However, the genome size is another parametric quantity that has to be taken into consideration since it plays an of import function in finding the coverage. Furthermore, another benefit of the Following Generation Technologies is the ability to sequence genomes at a lower cost since harmonizing to Mardis ( n.d ) ; the new engineerings are far cheaper. Despite being fresh in the market, the Following Generation Technologies have captured a just portion of the industry and are doing scientists to look at biological jobs in a different position ( Mardis, 2008 ) . In this reappraisal, a few chief commercial Next Generation Technologies are discussed and a comparing is made among them. A biological application utilizing the Illumina/Solexa Genome Analyzer is described and the challenges that conventional bioinformatics is confronting due to Following Generation Technologies are besides brought frontward.Following Generation DNA SEQUENCING TECHNOLOGIESRecently, there has been a major roar in commercially available package for genome sequencing. The most celebrated 1s are Roche, Illumina/Solexa Genome Analyzer, Applied Biosystems SOLiDTM System, Helicos HeliscopeTM and Pacific Biosciences SMRT ( Mardis, 2008 ) .Roche 454/ FLX pyrosequencerRoche 454 DNA sequenator was released in twelvemonth 2004 ( Mardis, 2008 ) .The first measure to sequence the DNA involves a library readying where the Deoxyribonucleic acid sample is fragmented into smaller pieces of approximately 400 to 600 base brace. After that, A and B adapters are attached to the Deoxyribo nucleic acid fragments which are so split into individual strands. The single strands now have A and B adapters attached to them. The DNA library fragments are placed upon really bantam agarose beads such that one bead relates to merely one DNA fragment ( Mardis, 2008 ) . PCR reactants and emulsion oil is added to the solution which is shaken smartly so that the Polymerase concatenation reaction can be initiated. The beads are normally isolated in single H2O micelles where the Deoxyribonucleic acid fragments get replicated bring forthing about one million transcripts of each DNA fragment per bead ( 454LifeSciences, n.d ) . The beads are so placed on a PicoTiterPlate which contains little Wellss ; one for each bead. The well is besides filled with gaining control beads which contain an enzyme which helps in the sequence by synthesis attack that Roche uses ( 454LifeSciences, n.d ) . Once this readying has been done, the PicoTiterPlate is loaded in the Roche 454 machine. After that, the 4 bases solutions are loaded in the machine and are washed over the home base consecutive in one sequencing tally. Once, the base starts to adhere with the DNA fragment, the enzyme in the bead detects the incorporation of the base and finally releases visible radiation ( Mardis, 2008 ) . This light signal is detected by a CCDA camera and is recorded on a flowgram. Normally, the sum of visible radiation produced is dependent on the figure of bases incorporated ( 454LifeSciences, n.d ) . Finally, a set of flowgrams is obtained and analysed to bring forth DNA sequences which are so mapped against a mention sequence for assembly.Illumina/Solexa Genome AnalyserIllumina sequencing can be broken down into three stairss. The initial measure starts with the library readying in which the Deoxyribonucleic acid sample is sheared into fragments of about 800 base braces and two specific arrange rs are ligated to each terminal of the fragments. The following stage is known as bunch coevals in which Illumina uses span elaboration PCR to bring forth multiple transcripts of the DNA. Illumina uses an 8 channel flow cell incorporating a immense sum of primers bounded to its surface. The individual stranded Deoxyribonucleic acid fragments are so bound at random in the surface of channels of the flow cell to make transcripts ( Staehling, 2008 ) . A series of unlabeled bases and enzymes are washed over the channels to get down the span elaboration procedure. The individual stranded fragments go dual isolated during the reaction and they are denatured to obtain individual isolated molecules. This rhythm is repeated legion times which ends in 1000000s of bunchs of DNA molecules found in the channels of the flow cell ( Staehling, 2008 ) . Once cluster coevals has completed, the bunch are now ready for sequencing, which is the last phase. The flow cell is so loaded in Illumina which se quences 1000000s of bunchs at the same time. In the first rhythm, fluorescently labeled bases are added and all of them compete to adhere to the templet. Once the incorporation takes topographic point, the remainder of the bases are removed and the bunchs are excited by a optical maser to acquire a image of the flow cell and observe the freshly incorporated base. This procedure is repeated several times. Base naming is used to place the bases in the sequence images as shown in Figure 1. A mention genome is besides used to ease sequencing and analysis ( Staehling, 2008 ) . Fig. . Stairss in Illumina Sequencing ( Goldstein, 2009 )Applied Biosystems SOLiDTM SystemApplied Biosystems DNA sequencing is divided into five stairss viz. sample readying, Emulsion PCR, Ligation, Imaging and Data Analysis severally. Two picks for sample readying are available viz. a fragment library or a mate-pair library. In both picks, the Deoxyribonucleic acid is sheared and arrangers are ligated to the fragments. A fragment library incorporates a individual piece of DNA fragment while a mate-pair library binds two pieces of DNA which are at a known distance in the sample. The libraries contain legion molecules and each molecule undergoes clonal elaboration under emulsion PCR. The sample is so enriched with magnetic beads which are so covalently bonded to a glass slide. Applied Biosystems provides the flexibleness to analyze one, four or eight samples per slide. The templet beads are so assorted with a cosmopolitan sequence primer, ligase and a batch of Di-base investigations. The latter are fluorescently labelled with four dyes. Each dye represents four of the 16 dinucleotide bases. The template sequence gets hybridised with the investigation and is ligated. Once fluorescence is measured, the dye is cleaved off go forthing a 3-5 premier phosphate for farther reaction. This procedure can be repeated n times to widen the read length which is usually 35 base brace ( Mardis, 2008 ) . The synthesised strand is removed and a new primer is formed which has a one base displacement and ligation rhythms are repeated. The primer reset procedure is repeated for 5 unit of ammunitions. Bar encryption and the decryption matrix is normally used to garner the sequenced informations for analysis ( Yutao et al. , 2008 ) .Heliscope TMHeliscope uses the individual molecular sequencing attack. The Deoxyribonucleic acid sample is cut in short lengths of about 100-200 base brace ( Wash & A ; Image, 2008 ) .A poly ( A ) priming cosmopolitan sequence is added to the 3 premier ter minal of each Deoxyribonucleic acid strand. Each strand is so attached to a fluorescent adenosine polynucleotide. The strands are so transferred onto the heliscope flow cell which contains many T gaining control sites that are spread on its surface. Each single DNA templet so hybridizes to the surface of the flow cell. The flow cell is loaded into the HeliscopeTM instrument and a optical maser enlightens its surface demoing the place of each fluorescently labelled templet. A CCDA camera is used to bring forth a map of the templets by taking multiple images of the flow cell in an organized manner. After imaging, the templet label is cleaved and washed off. Sequencing takes topographic point by adding DNA polymerase and any fluorescently labelled nucleotide to the flow cell. T gaining control sites service sequencing primers by the tSMS procedure ( Wash & A ; Image, 2008 ) . DNA polymerase speeds up the binding of the labeled bases to the set of primers harmonizing to the templet. A w ash up procedure removes the Deoxyribonucleic acid polymerase and any boundless bases. The recent incorporation is so visualised by lighting and imaging the flow cell surface. The cleavage is so removed and the procedure is repeated in the same manner for all the staying bases until the desired read length is achieved. Sequencing informations is gathered with each new base add-on. Using the tSMS procedure, every strand is alone and sequenced independently ( Wash & A ; Image, 2008 ) .Pacific Biosciences SMRTPacific Biosciences uses the individual molecule attack in a existent clip manner, hence SMRT. First, the single bases are labeled with a different fluorescent coloring material which is attached to the terminal phosphate alternatively of the base of the base. This characteristic allows the DNA polymerase enzyme to split off the fluorescent label when a base is incorporated. The undermentioned procedure emits light which can be captured in a nano-photonic chamber known as the Zero Mode Waveguide ( Metzker, 2010 ) . Nucleotides flow in and out of the chamber of the ZMW and when DNA polymerase initiates the incorporation of a base, it takes several nanoseconds during which its fluorescent label is excited and the visible radiation emitted is captured by a sensor. After adhering, the label is cleaved away and it diffuses off. The whole procedure is repeated and the different explosion of visible radiations corresponds to different bases which are recorded and analysed by research workers ( Metzker, 2010 ) .Comparison of the platformsTable.Comparison of the Following Coevals Platforms The mentions [ 1 ] and [ 2 ] refers to ( Gupta et al. , 2010 ) and ( Metzker, 2010 ) severally. There are some disagreements between the two documents refering the throughput, run clip and read length. Metzker states that one of the advantages of Illumina is the fact that it is widely popular which does non represent a truly strong point.Biological ApplicationNGS Technologies can be used to happen the places of nucleosomes with regard to DNA which can be helpful to understand their function in the ordinance of written text ( Schones et al. , 2008 ) .Schones et Al. ( 2008 ) describes the experimental processs in different phases. The first measure involved the readying of the nucleosome solution. In this stage, CD4 + T cells were incubated with anti CD3 and anti CD28 so as to trip the cells for 18 hours. After that, the T cells were treated with MNASE to bring forth the mononucleosomes. Deoxyribonucleic acid fragments of about 150 base braces in length were obtained from the agarose gel and ligated to the Solexa flow cells. These were so sequenced utilizing the Illumina/Solexa Genome Sequencing machine. The following stage involved the analysis of all the informations being generated from the sequenator. Solexa grapevine analysis was the first one to be carried out where sequenced reads of 25 base brace was mapped to the human genome ( hg18 ) and merely the duplicate 1s were kept and others discarded. Nucleosome marking was facilitated since the sequenced reads acted as an input in the marking map to bring forth a nucleosome profile. This was achieved by utilizing a skiding window of about 10 base brace. The following measure involved sorting cistron sets and this was achieved utilizing microarray experiments. Polymerase II procrastinating analysis was carried out in an mRNA-level based attack so as to place which cistrons contained stalled, elongated or no Polymerase II. The sequence reads were so modelled as a Poisson distribution of the whole genome to descry the sliding window with Polymerase II. Each cistron set was so aligned so as to analyse the Transcription start site found near the cistrons. Nucleosome degrees specific to a nucleosome place were so quantified by utilizing aligned reads and window values. At the terminal of the experiments, the consequences found by the research workers stated the nucleosome place relation to DNA had a direct correlativity with written text ordinance affecting RNA polymerase II binding. Some of the experiments consequences can be depicted in Figure 2, Figure 3 and Figure 4 severally. Fig. . Maping Nucleosome Positions by the Solexa Sequencing Technique ( Schones et al. , 2008 ) Fig. . Nucleosome phasing environing TSSs ( Schones et al. , 2008 ) Fig. Nucleosome Phasing near TSSs Is Correlated with Pol II Binding ( Schones et al. , 2008 )ChallengeFollowing coevals sequencing engineerings have so created a revolution refering DNA sequencing and has opened the doors to a new field which is really different from that of traditional sequencing methods. There is a ferocious competition between companies to bring forth up to day of the month, fast and dependable sequencing methods. However, despite all the advantages that NGS brought along, they still pose several challenges to the field of bioinformatics.Data DelugeFollowing Generation sequencing engineerings are taking at bring forthing immense sum of informations and at a lower monetary value ( Kircher & A ; Kelso, 2010 ) . In fact, it is even possible to contemplate the option of sequencing the whole genome of an being at merely $ 1000 in the close hereafter ( Pareek et al. , 2011 ) . All these new sequencing informations seems truly appealing at one terminal but considered sig nifier another point of position, it might go debatable in the long tally. The mere fact of cut downing the cost of sequencing or sequencing engineerings implies that sequencing will be easy accessible. This implies that, any research lab or even people at place would be able to sequence genomes. In this current epoch itself, information handling is rather boring with all the databases holding portion of the information and some non holding them at all. New organisational ways and protocols will hold to be defined to guarantee that there exists a consensus between all the information that will come pouring into the databases. Optimized filters will be needed to distinguish between debris informations, duplicated informations and equal informations. Even new databases or information warehouses will hold to be built to guarantee none of the information is wasted and everything has been kept in a standardized format.ResourcesThe fact that NGS is traveling at such a immense gait raises the inquiry of whether the current province of hardware and package will be able to manage the burden of information that it will be bring forthing. Fig. Historical tendencies in storage monetary values versus DNA sequencing costs ( Stein, 2010 ) The graph in Figure 4 denotes the rate at which the cost of DNA sequencing per $ is increasing every bit compared to that of the difficult disc storage. It can besides be seen that the NGS causes a immense displacement in the sum of informations per $ and even by-passing the rate of disc storage. This information is cardinal because it shows that disc infinite or storage of high throughput informations might go debatable in the close hereafter. More processing power and RAM will hold to be allocated to the NGS applications for them to run swimmingly. Cloud computer science can be a solution to this peculiar issue but it depends on the sum of information that is generated every bit good. If cloud computer science is brought in the image, so new algorithms and parallel computer science will hold to be implemented to manage this job.Huge assortment, less consensusNowadays, there is a broad assortment of commercially available NGS engineerings. However, there is no consensus about the re ad length, throughput or runtime of the bundles which can be demonstrated by Table 1. Choosing which bundle is optimum for sequence alliance sometimes go really boring since the truth of each is non definite and standardized. Developing even newer engineerings can make more havoc about truth, therefore the demand for standardisation foremost.DecisionNGS engineerings have provided a batch of installations in footings of Deoxyribonucleic acid sequencing to the life scientists. When compared to the Sanger sequencing, NGS engineerings sequencing is much cheaper and faster. Nevertheless, Sanger sequencing remains one of the basic pillars of DNA sequencing since the mistake rates and profiles are much less as compared to that of NGS engineerings ( Kircher & A ; Kelso, 2010 ) . Equally long as the genome will stay a enigma to the scientists, the coming of following coevals engineerings will go on in order to decode the familial codification.

Monday, January 6, 2020

Army Value Integrity - Free Essay Example

Sample details Pages: 2 Words: 627 Downloads: 1 Date added: 2018/12/14 Category Security Essay Type Argumentative essay Level High school Tags: Army Essay Military Essay Did you like this example? Over the decades, the seven army values have been the rock backbone of the United States army. On the other hand, the values have been the defining aspect of good soldiering as the soldiers and their leaders live by the seven core values. To simplify the vales, they are regarded using the acronym LDRSHIP which represents the values as; Loyalty, Duty, Respect, Selfless, Service, Honor, Integrity and Personal Change (Army Refocuses on Seven Core Value 4). Don’t waste time! Our writers will create an original "Army Value: Integrity" essay for you Create order Being an army officer is a job that one as a soldier must uphold with diligent by both men and women in the army. The basic values are taught in training and reinforced all through their varying training drills as well as through a soldiers military career. This essay discusses integrity, and its relevance in military as one of the core values in the Army. According to me, integrity is of considerable importance to the success of an army officer as well as the entire army troop. Doing what is right, even when no one is keeping watch is what is known as Integrity. In military, integrity is one of the army values. According to Tarcza (77), integrity is regarded as the aspect of an individual being honest as well as having strong moral principles. This is one of the expensive values as integrity demands one to be honest in terms of professional and personal relationships. More so, one need to be trustworthy, which in turn inspires trust among people around someone. Honesty demands one to be responsible for every action he/she undertakes as well as always act professionally. In the military, a soldier is supposed to have integrity and pride so as to serve his country honorably. Once the desire to be honorable is lost, a soldier cannot become a professional as well as prospective leader in the military. Being integrity goes beyond doing the right thing when no individual is watching. Adherences to moral/ethical principles as well as pursuit of undiminished condition are two key aspects that ensure integrity is an essential value for a military officer. Through integrity, strength of character is gained as well as the ability for an individual to learn from self-mistakes and focuses on self-improvement. Being an intrinsically motivated thing, integrity helps an individual toward ethical behavior (Matelski 80). With increased diversity in terms of occupation within the military, integrity, value enables a military officer to succeed in any sector within the forces. I.e., either one is the leader, a soldier in the battle, a mechanic, doctor, engineer or any other field, the soldier is able to perform his work within minimal supervision as a result of self-acquired integrity. According to Matelski (78), success without integrity isnt a genuine success. This is due to the fact that, a person with integrity makes value-based decisions, and not decision focused on personal gain. For soldiers focused to be leaders, whether in their team, in a camp or the overall military leader, integrity is a paramount value for good and an effective leadership. Over the years, the need to maintain integrity has remained quiet a task. Breaching of integrity severely hurts a military soldier overshadowing previous success. Breaches of integrity and the resulting consequences are a bitter reminder of the major role and importance of integrity. In summary, integrity remains an important value for an army officer. However, together with the other 6 values, they are contributing to making of a complete army officer. Being a soldier, integrity is an important value for an army to possess. Works cited Army Refocuses on Seven Core Values.? Army Reserve Magazine, vol. 44, no. 3, Fall98, p. 4. Matelski, Thomas R. Growing Army Professionals.? Military Review, vol. 96, no. 5, Sep/Oct2016, pp. 76-83. Tarcza, Kenneth. The Army Values Challenge.? Military Review, vol. 81, no. 1, Jan/Feb2001, p. 77.